time 3-4 hours
It is possible to do in one playthrough but pay attention to collectibles and don't use med kits. Do a lot of manual saves. You can die but not use your d-pad
Kill first three nossalises melee, than you can die to not waste your hp. The trophy still will be yours. Finally do the hidden trophy (it is not huge spoiler but it can be for some of you guys) If you mess up with collectibles, there is not chapter select (whole dlc is just another chapter like in base game) so you may need another partial playthrough like me.